UIC Proof of Concept (POC)

The Proof of Concept Awards Program was launched by the UIC Office of Technology Management (OTM) in early 2012 to advance early stage research that taps into the talent and innovations at UIC in order to benefit the broader community. The UIC Innovation Fund was established in 2020 by the UIC Office of the Vice Chancellor of Innovation (OVCI). The UIC POC Awards Program now falls under the UIC Innovation Fund umbrella and is managed in partnership between OVCI and OTM to bridge a gap between basic research and commercialization.

The UIC POC funds will be available to support proof of concept innovations emanating from UIC research. Selected proposals will receive initial funding of up to $50,000 to develop research projects with commercial potential. Upon successful completion of milestones from the initial funding, projects may be eligible to receive up to an additional $150,000. Final award amount will be determined by the scope of work and contingent upon successful completion of milestones developed according to input from selection committee.

The aim of the UIC Proof of Concept (POC) Awards Program is to accelerate the commercialization of technologies being developed at UIC by helping to bridge the funding gap that often exists between translational research and commercialization. The outcome of a UIC POC award should demonstrate commercial viability and position the technology for industry or investor engagement.

UIC Innovation Fund

The UIC Innovation Fund has been established at UIC in partnership between the Office of the Vice Chancellor of Innovation and the Office of Technology Management with a goal to position UIC as a leader in technology acceleration. The Innovation Fund links emerging technologies, federally funded innovation grants, alumni, donors, corporations, investors and the greater community to improve commercialization potential.  To learn more about the UIC Innovation Fund, and to stay updated on new developments and announcements please check out the Vice Chancellor of Innovations’ website: https://innovation.uic.edu/initiatives/.

Apply for the Proof of Concept Award

August 8, 2025 – Application Opens
September 8, 2025 – Applications Due (5pm CST)
Week of TBD- UIC POC Finalists Announced
Week of TBD – Final Pitch Day
Week of TBD – UIC POC Winners Announced

Interested in applying for a POC Award? Specific details for submitting a proposal are below. Applications open August 8th, 2025 and will close on September 8th ,2025 at 5pm.

Project Criteria

The aim of the UIC Proof of Concept (POC) Awards Program is to accelerate the commercialization of technologies being developed at UIC by helping to bridge the funding gap that often exists between translational research and commercialization.

Projects must be focused on commercial product development or testing. The outcome of a UIC POC award should demonstrate commercial viability and position the technology for industry or investor engagement.

Project criteria:

  • Strong protectable IP
  • High commercial potential
  • Low execution risk
  • milestones

POC funding cannot be used for basic exploratory studies or as general funding for the PI’s lab. Project proposals should address how achieving identified project milestones will move the invention towards commercialization.

Scope of Award

Phase I projects will receive up to $50,000 over a six-month period to develop a technology or invention towards important milestones critical for commercialization.

Projects that successfully complete Phase I milestones may be eligible for Phase II funding. NOTE: At this time, Fall 2025 applications will only be considered for Phase I project funding.

Phase II awards provide up to $150,000 over a 12-month period to support further development of completed Phase I projects.

Final award amount will be determined by the scope of work and contingent upon successful completion of milestones developed according to input from selection committee.

In addition to funding, selected projects will receive support from the Office of Technology Management to provide guidance on commercial development including market landscape, IP analysis, and industry feedback on commercially relevant milestones.

Applicants must be full-time UIC faculty, staff, and researchers with dedicated research space and resources and have an invention disclosure on file with the Office of Technology Management. The invention disclosure must be submitted prior to the submission of a POC pre-proposal. Forms and instructions on disclosing a technology can be found here: OTM Submit your idea. Any questions, please contact a technology manager.

The technology or invention the proposal is based on must not be exclusively licensed or encumbered by any other prior obligations that would prohibit commercialization.

Only applicants who meet and agree to the following criteria will be considered eligible to submit a Pre-Proposal Application:

  1. Principal Investigator (PI) must be a full-time UIC faculty member or emeritus faculty with active University research labs.
  2. The PI must have an invention disclosure on file with the UIC Office of Technology Management (OTM), upon which the proposed project will be based, prior to applying. Applications will not be accepted if a disclosure is not on file with the OTM prior to the application deadline.
  3. The technology, which provides the basis for the project proposal, must not yet be licensed or optioned to a third-party.
  4. The intellectual property (IP) surrounding the invention disclosure must be owned by the University of Illinois. Please contact the Office of Technology Management if you are unsure of the intellectual property ownership of your invention. If IP is jointly owned with another institution, an inter-institutional agreement (IIA) must be in place with UIC designated as the commercialization lead.
  5. The proposed project must be focused on commercial product development or testing. POC Awards Program funding cannot be used for basic exploratory studies or as general funding for the Principal Investigator’s lab. Projects must focus on a current invention disclosure on file with the OTM and should address how achieving identified project milestones will move that invention towards commercialization.
    Only one POC Awards Program project may be submitted per PI as a lead.
  6. Investigators with multiple technology disclosures should focus their proposal on the most commercially promising technology within their portfolio.
  7. All project milestones for Phase I should be achievable within 6 months of the start of funding and within the requested budget.
    If you are a previous POC Awards Program winner and your project is still in progress and (or) still receiving POC Awards Program funding, you are in-eligible to apply.
  8. You must adhere to the template and character limitations in the pre-proposal. Any characters over the maximum allowed will be deleted and not evaluated.
  9. By submitting this application you acknowledge that this project is eligible for submission based on the criteria set forth in this application. You further understand that if invited to submit a Full Proposal Pitch Presentation, there is no guarantee that the Full Proposal will be funded.
  10. The Full Proposal Presentation will be reviewed and evaluated by an External Review Committee and only those projects which are selected by the Committee will be funded at the levels recommended by the committee.
  11. In order to be eligible for Phase II funding, Phase I awardees must successfully complete their Phase I by the specified end date and submit a Phase II Proposal Presentation to be reviewed by an External Review Committee.
  12. Previous POC Awardees are not eligible for Phase II Awards, though they are welcome to submit a new project for consideration in Phase I.
  13. Awarded funds may not be used to cover salary expenses (with the exception of graduate assistant or graduate hourly salaries for students working directly on the approved POC project.

To apply, investigators must submit an application.

The application requests the following:

  • Technology Background – Present a high-level overview of your technology and how it will address a problem in the market.
  • Rationale and Significance – Describe the technical rationale behind your studies.
  • Key Studies – List 3-5 key steps/studies you need to achieve in order to demonstrate and validate commercial viability for Phase I of the study. Success parameters and an estimated budget should be provided for each step or study listed.
  • Project Risk and Mitigation – Identify current technical or commercial risks associated with your technology and how your proposed project will address these risks and thus, significantly impact the commercial potential of your technology. Also, describe how the commercial competitiveness of your technology will increase after the proposed project is successfully completed, and what your next steps are in the development/commercialization process.
    • Competitive Advantage – Describe the technology’s development to date. Explain what will differentiate your technology in the market place and create a competitive advantage for your product. Also, provide any industry-specific feedback that you have received on the competitive advantage of your technology and its ability to fulfill an unmet need in the marketplace.
  • Appendix – A maximum of one page of supporting data or references may be included.

Applications are reviewed by an internal committee composed of UIC faculty, technology managers from the OTM, and other select individuals from across the campus. Applications are evaluated based on scientific merit and the feasibility of completing the project within the requested budget and timeframe.

Selected applicants will be asked to present a pitch of their proposal, which will consist of:

  • PowerPoint presentation
  • Detailed budget

Finalists will participate in project planning meetings and mock pitches with the Office of Technology Management as they prepare for the final pitch day presentation. Selected finalists will have an opportunity to pitch their proposal to an external review committee of industry and investment experts.

The final presentation review committee will be a multidisciplinary committee of scientists, industry professionals, and investors, from outside of the University. POC awardees will be selected based on the project’s ability to successfully prepare the technology for commercialization within the scope of the proposed studies and within the requested budget and timeframe.

Previous POC Awardees

Year Awardees
2024
  • Alex Leow College of Medicine and College of Engineering Project Title: Using Natural Language Processing and AI on your Smartphone to Gain Mental Health Insights
  • Alexander Adibekian College of Liberal Arts and Sciences Project Title: A Minimal Size Covalent-Reversible Tag for in vivo active LYTACs
  • Andrei Gartel College of Medicine Project Title: Novel FOXM1 Inhibitor against Human Cancer
  • Arunkumar Subramanian College of Engineering Project Title: Plasma Beam Lithography
  • Bin He College of Medicine Targeted Project Title: Delivery for Cancer Immunotherapy
  • Brad Merrill College of Medicine Project Title: Next Generation of CRISPR Stem Cell Programming
  • David X. Marquez College of Applied Health Sciences Project Title: Advancing the BAILAMOS Dance Program
  • Kamran Avanaki College of Engineering Project Title: Wearable Blood Gas Analyzer
  • Mathew T. Mathew College of Medicine Rockford Project Title: Electrochemical, Nanoengineered, and Intelligent Biosensor for Detection of Pancreatic Cancer
  • Pai-Yen Chen College of Engineering Non-Hermitian Cryptographic Primitives for Internet-of-Things Security
  • Stephanie Cologna College of Liberal Arts and Sciences Project Title: Sigma-2 receptor as a Target for Niemann-Pick Type C
  • Zongmin Zhao College of Pharmacy Nanoengineered Project Title: Dendritic Cells for in situ Immunization against Glioblastoma
2022
  • Ramaswamy Kalyanasundaram and Justin Richner College of Medicine Project Title: Developing a novel mRNA vaccine for lymphatic filariasis and testing it in cell lines and in a mouse model
  • John Monaghan College of Liberal Arts and Sciences Project Title: Spatial and Temporal Modeling of Aircraft Crash Survivor Behavior
  • Terry Moore and Dustin Fraidenburg College of Pharmacy and College of Medicine Project Title: Non-covalent NRF2 activators for pulmonary arterial hypertension
  • Sangil Kim College of Engineering Project Title: Development of Prototype Pouch Cells for High-Performance, Long-Lasting All-Solid-State Batteries Based on Zwitterionic Polyurethane Electrolytes
  • Bellur S. Prabhakar College of Medicine Project Title: Diabodies to Treat Autoimmune Diseases
  • Pavel A. Petukhov College of Pharmacy Project Title: Novel inhibitors of thioredoxin glutathione reductase (TGR) for the treatment of schistosomiasis
  • Phase II

    Deepak Shukla College of Medicine Project Title: DECON: A New Technology to Treat Herpes
  • Meenesh R. Singh College of Engineering Project Title: Fully automated robotic system for effective screening of drug substance
2021
  • Leslie Aldrich Department of Liberal Arts and Sciences Project Title: Optimization and evaluation of an autophagy-selective inhibitor for cancer therapy
  • Deepak Shukla College of Medicine Project Title: DECON: A novel platform for enhanced antiviral drug delivery
  • Meenesh Singh College of Engineering Project Title: Fully automated robotic system for effective polymorph screening of drug substance
  • Arunkumar Subramanian College of Engineering Project Title: IC-compatible, direct deposition of patterned nanostructures using physical vapor deposition techniques
  • Joe Zhou College of Medicine Project Title: Three-dimensional functional MRI (fMRI) in focused brain regions

    Phase II

  • Paul Goldspink College of Medicine Project Title: Targeting cardiac troponin I for treatment of cardiac myopathies
  • Reza Shahbazian-Yassar College of Engineering Project Title: Commercially viable coating based on graphene oxide nanosheets for dendrite-free lithium metal batteries
2020
  • Paul Goldspink College of Medicine Project Title: Targeting 14-3-3/Troponin I in Cardiomyopathy
  • Russell Pesavento College of Dentistry Project Title: Coated Nanoceria as a Caries Prevention Agent
  • Justin Richner College of Medicine Project Title: Dengue virus mRNA vaccine
  • Fei Song and Jeffrey Loeb College of Medicine Project Title: GlyB4 biologic for neurodegenerative diseases
  • Alexander Yarin and Youngkwan Song Colleges of Engineering and Nursing Project Title: Medical device-related pressure injury prevention pressure-indicating material
2019
  • Ayman Al-Hendy College of Medicine Project Title: TLR5: Molecular Bio-Imaging Probe to Differentiate Uterine Fibroids from Sarcoma
  • Gang Cheng College of Engineering Project Title: Commercialization of an Anti-infective Urinary Catheter
  • Gus Cho College of Medicine Project Title: Peptide Treatment of Vascular Occlusion in Thromboinflammatory Disease
  • Reza Shabazian-Yassar College of Engineering Project Title: A Commercially Viable Coating Based on Graphene Oxide Nanosheets for Dendrite-Free Lithium Metal Batteries
  • Phase II

    Bin He College of Medicine Project Title: Viral Immunotherapy of Cancer
  • Sandeep Jain College of Medicine Project Title: Immunotherapy of Dye Eye Disease
  • Sangeetha Madhavan College of Applied Health Sciences Project Title: DIG-I-PRIME™ to Enhance Stroke Neurorehabilitation
  • Ajay Maker College of Surgery Project Title: A Novel Single Platform Screening Test for Early Stage Pancreatic Cancer
2018
  • Mark Rosenblatt College of Medicine Project Title: Intraocular display projector for corneal blindness
  • Sangeetha Madhavan College of Applied Health Sciences Project Title: SMART ankle-foot motion tracker device for neurorehabilitation
  • Ajay Maker College of Medicine Project Title: A novel single platform screening test for early stage pancreatic cancer
  • Amit Trivedi and Theja Tulabandhula College of Engineering Project Title: Delivering robust, real-time artificial intelligence (AI)
  • Sandeep Jain College of Medicine Project Title: Treatment of citrullination-related eye diseases
  • Bin He College of Medicine Project Title: Oncolytic immunotherapy of cancer
  • Phase II

    Rui Xiong and Gregory Thatcher College of Pharmacy Project Title: Novel oral treatment for metastatic ER+ breast cancer
  • Arnon Lavie College of Medicine Project Title: TRAIL-asparaginase fusion protein as a novel pancreatic cancer therapeutic
2017
  • Mary Jo LaDu College of Medicine Project Title: Novel Mechanistic Biomarker for Alzheimer’s Disease in Human Plasma
  • Arnon Lavie College of Medicine Project Title: TRAIL-Asparaginase fusion protein as a novel pancreatic cancer(PC) therapeutic
  • Jason McAnany College of Medicine Project Title: Apparatus and method for noise-based visual
  • Besma Smida and Danilo Erricolo College of Engineering Project Title: Inherent Self‐interference Cancellation for In‐band Full-duplex Wireless Communications
  • Rui Xiong and Gregory Thatcher College of Pharmacy Project Title: Novel Brain-Penetrable, Oral SERDs for ER+ Breast Cancer
  • Phase II

  • Kaori Yamada College of Medicine Project Title: 23 aa Peptide Derived From Kinesin KIF13B Inhibits Angiogenesis: Novel Therapy for Ischemic Diseases
2016
  • Marcelo Bonini College of Medicine Project Title: Mito-spyro, a new mitochondrial targeted antioxidant with anti-cancer, anti-arrhythmic and potential anti-diabetic functions
  • Alan Mancini College of Pharmacy Project Title: Formulation of Topical Glyburide for Use in Diabetic Wound Care Treatment (Topical Glyburide for Wound Healing)
  • Igor Veryovkin College of Liberal Arts and Sciences Project Title: Right Angle Ion Mirror-Prism (RAIMP) for High Resolution Mass Spectrometry Imaging
  • Kaori Yamada College of Medicine Project Title: 23 aa Peptide Derived From Kinesin KIF13B Inhibits Angiogenesis: Novel Therapy for Ischemic Diseases
  • Phase II

    Terry Vanden Hoek College of Medicine Project Title: Phase II-Novel TAT-peptide Improves Sudden Cardiac Arrest (SCA) Survival
2015
  • Shiva Shahrara College of Medicine Project Title: TLR5: A Novel Treatment Strategy for RA Patients
  • Shane Phillips College of Applied Health Sciences Project Title: Wearable Continuous Cardiovascular Sensor and Algorithm for Healthcare & Rehabilitation
  • Amin Salehi-Khojin College of Engineering Project Title: An Advanced Li-Air Battery Cell for Energy Storage Applications
  • Steven Ackerman College of Medicine Project Title: Peptide Nanoparticle Inhibitor of CCR3-Mediated Eosinophilic Inflammation in Asthma
  • Terry Vanden Hoek College of Medicine Project Title: Phase I-Novel TAT-peptide Improves Sudden Cardiac Arrest (SCA) Survival
  • Maria Siemionow College of Medicine Project Title: Phase I-Novel Chimeric Cell Therapy for Treatment of Duchenne Muscular Dystrophy
  • Arnon Lavie College of Medicine Project Title: Phase I-Novel L-Asparaginase Cancer Drug: Clone 63
  • Brian Chaplin College of Engineering Project Title: Phase I-Commercialization of Reactive Electrochemical Membranes (REMs)
2014
  • Brian Kay College of Liberal Arts and Science Project Title: High-Throughput Antibody Generation by PExSR
  • Valerie Dobiesz and Stacie Geller College of Medicine Project Title: Obsterical Medical Device for Auto Transfusion in Post-Partum Hemorrhage (PPH)
  • Sriram Ravindran College of Dentistry Project Title: Bioenhanced Implant Surfaces for Improved Osteointegration
  • Mark Grechanik College of Engineering Project Title: Making Cloud Computing Elastic, Cost Effective and Efficient
  • Bellur Prabhakar College of Medicine Project Title: Evaluation of Soluble OX40L-JAG-1 to Treat Type-1 Diabetes
  • Dieter Klatt Colleges of Engineering and Medicine Project Title: Validation of In-Vivo SLIM-MRE
  • Sudip Mazumder College of Engineering Project Title: Wide-Bandgap Optical Emitter Turn-Off (ETO) Thyristor
  • Mahshid Amirabadi College of Engineering Project Title: High Power Density Power Conversion System
  • Mary Jo LaDu College of Medicine Project Title: Novel Biomarkers for Alzheimer’s Disease in Human Plasma
  • David Peace College of Medicine Project Title: Peptide Targeted Immunotherapy of Prostate Cancer
  • Anantha Harijith College of Medicine Project Title: PF-543, a Novel Drug to Treat Oxidative Lung Injury
  • Alan Kozikowski College of Pharmacy Project Title: Use of 5-HT2c-Agonists in Rett Therapy
2013
  • Venkat Venkatakrishnan College of Engineering Project Title: Security Analysis of Online Enterprise Websites
  • Amin Salehi-Khojin College of Engineering Project Title: Novel Catalysts for Syngas Production by CO2 Reduction
  • Nadim Mahmud College of Medicine Project Title: Expanded Cord Blood as an Off-the-Shelf Bridge Graft to Augment Blood Cell Numbers
  • John Hetling Colleges of Engineering and Medicine Project Title:Detecting Glaucoma Where it Starts
  • Sandeep Jain College of Medicine Project Title: New Drug for Treating Dry Eye Disease – Phase I/II Human Trial
  • Ying Liu College of Engineering Project Title: Scalable Process for Manufacturing Nanoparticles Encapsulating Hydrophobic Compounds
  • David Carley College of Engineering Project Title: Proof of Concept for Real‐Time Prediction of Driving Performance and Safety
  • Alexander Aruin College of Applied Health Sciences Project Title: Design and Optimization of Gait Performance Enhancing Insole
  • Shaolin Yang College of Medicine Project Title: Two-Dimensional J-Resolved LASER and semi-LASER Spectroscopy
  • Girish Deshpande Department of Medicine Project Title: Bench Testing of SecureTube
2012
  • Samuel Dudley College of Medicine Project Title: A Blood Test to Differentiate Systolic from Diastolic Heart Failure
  • Xavier Llor College of Medicine Project Title: Development of a Blood Test for Colorectal Cancer Screening Using a miRNA Panel
  • Hayat Onyuksel College of Pharmacy Project Title: A Novel Targeted siRNA Delivery Platform Case Study : Liver Fibrosis
  • Katherine Warpeha College of Liberal Arts and Sciences Project Title: Transformation of Critical Crops to Engineer Improved Stress and Yield Characteristics
  • Sohail Murad College of Engineering Project Title: Water Desalination by an Electric Field Enhanced Ion-Exchange Process
  • Mahnaz Shahidi College of Medicine Project Title: EyeFlow: A Device to Detect Impaired Cerebral Blood Flow
  • Farhad Ansari College of Engineering Project Title: Crack Sensor
  • Ramaswamy Kalyanasundaram College of Medicine Project Title: Improving the Current Lymphatic Filariasis Disease
  • Seungpyo Hong College of Pharmacy Project Title: Development of Biomimetic Device for Detection of Circulating Tumor Cells
  • Gregory Thatcher and Debra Tonetti College of Pharmacy Project Title: Selective Estrogen Mimic (Sem) Treatment of Tamoxifen-Resistant Breas